MACS (Magnetic Activated Cell Sorting)

MACS a New generation best quality sperm selection system it separated the best functional healthy sperms to improve pregnancy rate.


A good genetically robust sperm is essential for a normal embryo development. Sperms with high level of DNA fragmentation can damage the embryo development (blastocyst arrest) & can cause early miscarriage.

DNA damage represented by fragmentation & subsequent sperm Death (Sperm apoptosis) may be a cause of male infertility that standard test cannot identify.

Sperm DNA damage major cause is Oxidative stress (an imbalance between the production of free radicals & the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants.) Oxidative stress is increased by below factors;

  • Increasing Age
  • Inflammatory infections
  • Cigarette smoking (nicotine)
  • Illegal drugs
  • Exposure to High pollution
  • Elevated testicular temperature.

Thus MACS system is used to selectively remove these defective sperms ( morphologically impossible to separate).

The procedure uses advance magnetic labelling for defective sperms, when the semen sample is passed through the a isolated advance magnetic column the bad/defective sperms are separated from the good/healthy sperms & these good sperms are later used for ICSI or Freezing (Cryopreservation)

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